1. Quality: Uncompromising quality second to none. Products are manufactured by one of the most experienced and reputable pharmaceutical companies. (G.M.P. standard.) Quality is further verified by independent regular testing at our own cost.

 
2. Purity: Employ only the highest grade raw material or ingredients

 
3. Efficacy: Products are formulated with the most effective and clinically proven phytonutrients, botanicals, and antioxidants to achieve the desired effect.

 
4. Cost Effectiveness: Economical and affordable products of proven efficacy to optimize health and disease prevention with minimal side effects.

 
5. Simple dosing

 
6. Continued Education: We continue to provide the latest unbiased, reliable, clinical research findings to the public and assisting them to take charge of their own health using natural ingredients, vitamins or phytonutrients.

Enclosed is a list of references of medical textbooks ^{1, 2, 3}  and authoritative journals ^{4 - 12}  describing the role of vitamins, trace minerals, and phytonutrients at their therapeutic doses in the prevention and treatment of cardiovascular accidents (C.V.A.), myocardial infarctions (M. I.) ^{4, 5, 14, 17}, certain cancers ^{1c, 6, 7, 8} , and Alzheimer's disease ^{9, 10}. In addition, their mechanism ^{1a, 1b, 30, 31}  and mode of action ^{1c, 1d, 4}, as well as their effectiveness are clearly illustrated ^4-33.
 
As always, there will be a range of diverse opinions for any research and data published.  However, the evidence for vitamins and phytonutrients are overwhelming and can not be ignored.  Based on our clinical experiences and supported by the latest research, Ultra-Vit Plus has been newly formulated at the optimal synergistic doses (although its individual ingredients have been in use for many years).  The efficacy in disease prevention and the lack of side effects of the unique ingredients in Ultra-Vit Plus are well known and thoroughly researched and supported ^1-28.  Their cost effectiveness and safety profiles will set a new standard and play a crucial role in preventive medicine.

Each ingredient has specific sites of action in various metabolic pathways thus
providing remarkable and rapid benefits towards the maintenance of health.  However, when combined in a group, they become even more powerful.

The ingredients are clearly synergistic:

1) Vitamin E & Vitamin C ^{1a, 1b, 1c, 4, 21}

They are coupled in reducing oxidative stress which is the basic underlying
pathophysiology of atherosclerosis.  They resist lipid peroxidation, which produce
endothelium dysfuction  ^{12, 13}  of coronary cerebral arteries in heart attacks ^{4, 5} and strokes and helps to prevent Alzheimer's disease ^{9, 10, 11.}

Prospective studies of vitamin E supplement alone have shown to reduce major
cardiovascular events ranging from 35% to 40% ^{25, 26}.  Furthermore, controlled double blind studies with vitamin E supplement showed a 77% reduction in non-fatal myocardial infarctions ²⁸.  Significant regression of carotid stenosis was also demonstrated in a 5 year study with vitamin E supplementation ²⁹.

Vitamin E and C supplements together display an even more powerful protective
effect.  They have been proven to:

1. reduce coronary artery lesion progression angiographically ⁵,
2. completely reverse endothelial dysfunction of coronary arteries induced by homocysteine ¹⁴ ; and,
3. reduce high risk preclampsia by 53% through its protective effect on arteries ²³.

They form integral parts of the endogenous glutathione system that is the most
important, naturally occurring antioxidant defense entity in our body.

Glutathione is a tripeptide which has selenium and vitamin E as cofactors ^{1, 32}. It
prevents free radical damage to DNA ^{1d, 31, 39}  which leads to mutations and cancerous changes ^{6, 7, 8}.

Vitamin E and calcium supplements are associated with reducing colon cancer ⁷,
while selenium supplement alone reduces prostate, colorectal and lung cancer by 63%, 58% and 46 respectively ⁶.  This finding was confirmed ^8b  and consistent with other studies and trials ⁶.

3) Folic Acid & Vitamin B₁₂  ^{1a, 1c,  3,  6 , 7 ,  8}

These B complexes are required for many metabolic biochemical functions.  They
help to ensure normal cell division as well as DNA and RNA synthesis.  They are also essential in the production of red blood cells and key chemicals in the brain and in the maintenance of the myelin sheath.  Deficiencies are likely in the elderly due to decreased absorption and an unbalanced diet.

They lower homocysteine levels which itself is an independent risk factor for   
cardiovascular events ¹⁷ , stroke, peripheral vascular disease ¹⁴ and possibly Alzheimer's disease ^{16, 24}.

They may ward off certain cancers ^{7, 15, 16}  including lung, colon, rectal and cervical
and have been used in conjunction with other cancer chemotherapeutic agents ³³.
 

4) Vitamin P (Proanthocynidin) ^{19, 20, 21} & Vitamin E

They maintain vascular integrity and are powerful antioxidants 34 against lipid
peroxidation in the brain, which is generally accepted as the basic pathology of
Alzheimer's and age-related diseases. ^{10, 16,19,20}. Proanthocynidins recycle vitamin C
which in turn can recycle vitamin E. It has powerful protective anti-platelet and anti-
inflammatory properties by inhibiting 5-lipoxgenases ^14.35 and angiotensin - converting enzymes without the risk of bleeding.  It enhances the endothelial function of arteries against atherosclerosis ³⁶. In addition, it protects skin and capillary damage associated with the aging process by inhibiting elastase and collagenase enzymes ²⁰.

Vitamin E prevents ⁹ and slows down the progression of Alzheimer's diseases by
preventing oxidative damage as well as by reducing neuronal damage ¹¹. It has been proven effective in clinical trials ^{9, 10} and confirmed in independent research at Harvard, Queens University and McMaster University ^{2, 22}.